Molecular Epidemiology Approach Towards Pancreatic Cancer (PaC)

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Project Summary

Molecular pathological epidemiology (MPE) has contributed to the better understanding of several neoplastic diseases . By connecting putative etiological factors to specific molecular signatures across tumour phenotypes, the MPE approach can yield more accurate risk measures regarding PaC. Towards this broad goal, a case-control study will be conducted first on patients with different types of pancreas cancer and pancreatico-biliary diseases to identify associations among potential risk factors and PaC diagnosis and prognosis.


Project population

Patients within Barts Health NHS Trust


Project cohort

Patients with pancreatic cancers and pancreatico-biliary diseases attending at the hospitals or reported in the GP data since 2010.


Project criteria

Full GP dataset to include:

  • General
  • Diagnosis
  • Symptoms
  • Medical history
  • Lifestyle
  • Physical exam
  • Family history
  • Blood test
  • Urine test
  • Surgical procedures
  • Medication-SNOMED


Data state

Anonymised


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